ASP Source – Jon Otero

Using the Academic Search Premier, I found an article that addresses some issues with current methods of eradicating polio from the world by using OPV.

The link to the source

“Moreover, the possibility of vaccination with OPV causing VAPP, cVDPV and iVDPV leads to what is called the “OPV paradox”: OPV is necessary to eradicate the virus, but as long as OPV is in use, eradication cannot be achieved [12]. The majority of high-income countries and an increasing number of middle-income countries have switched to the use of full IPV or IPV–OPV sequential immunization schedules to avoid the risks of VAPP [13]. However, for developing countries, IPV use is not recommended in the WHO position paper published in 2003 [6]. The reason for this position was the insufficient data available on IPV effectiveness and logistical implications, preventing fully informed long-term policy decisions on the introduction of IPV for routine immunization in tropical developing countries [7]. A supplement to the WHO position paper from 2006 states that the continued routine use of OPV is ultimately incompatible with eradication of polio”

Although my other post supported the argument that Polio eradication is indeed achievable, this new information suggests the contrary. With the current means of immunization, OPV, global eradication of Polio is not achievable. It is likely that a mutated form of the virus, immune to antibodies, will infect the recipient of the OPV and spread that mutant strain.

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1 Response to ASP Source – Jon Otero

  1. davidbdale's avatar davidbdale says:

    I love your source, Jon, and you’ve made good use of it here. In particular, your quote is very much in keeping with the theme of counterintuitivity. Any paradox that includes the infuriating claim that good cannot be achieved without using a technique that insures the effort will fail is extremely counterintuitive.

    I want to caution you against overconcluding, however. You recognize now that you may have drawn too hasty a conclusion based on your first source. Don’t now make the same mistake by concluding that eradication is impossible. You say polio can’t be eradicated “with the current means available,” but isn’t it true that polio has in fact been eradicated from most of the countries in the world? Outbreaks are of course very frustrating, but not every claim in the source you provide supports your new conclusion.

    The availability of IPV, and the effectiveness of IPV, are different from “having sufficient data” about its effectiveness.

    The fact that IPV use “is not recommended” is not the same as claiming that IPV would not be effective in eradicating polio.

    Do you see what I mean?

    Nice work overall. Grade Recorded.

    Like

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